Abstract
Ribosomes from guinea pig liver, Cavia cobaya; frog liver, Rana pipiens; midgut of the silkworm, Bombyx mori; an earthworm, Lumbricus terrestris; a bacterium, Escherichia coli; a fungus of the genus Lactarius; and also the synthetic polyribonucleotides poly A and poly U were serologically compared with the cytoplasmic polyhedrosis viruses from Bombyx mori, the tent caterpillar Malacosoma disstria, and the tussock moth Orgyia leucostigma. The method of double diffusion on cellulose acetate membranes was used. Extensive cross-reactivity was observed, and it is attributed to the ribose phosphate backbone of RNA as a common antigen.
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