Abstract
Although lipid peroxidation by lipoxygenases usually results in a site-, stereo- and enantio-specific mechanism, it was found that the oxidation of phospholipids incorporated into the liposomal membrane by soybean lipoxygenase, but not by rabbit reticulocyte 15-lipoxygenase, was proceeded entirely by a nonspecific mechanism. The radical-scavenging antioxidants such as α-tocopherol did not inhibit specific oxidation; however, they did suppress the nonspecific oxidation.
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