Abstract
SummaryVaccination with viable or heat-killed oral anaerobic gram negative cocci (genus Veillonella) increased the resistance of a strain of Swiss-Webster mice to the lethal effects of veillonella endotoxin. Protection was best conferred with serologically specific endotoxin prepared from the strain of veillonella used for vaccination. Utilizing weight loss to sublethal dosages as a measure of biological effects of endotoxin, the duration and extent of weight loss in vaccinated mice is also considerably reduced as compared to nonvaccinated animals. Vaccination with heat-killed veillonellae significantly protected B. pertussis-sensitized mice against veillonella endotoxin, but not against lethal doses of E. coli endotoxin, histamine, or serotonin.Vaccination of mice with another oral gram negative bacterium (Fusobacterium) did not protect pertussis-sensitized mice against the lethal effect of veillonella endotoxin.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
