Abstract
Bradykinin (BK), a nonapeptide derived from kininogen, is involved in a variety of biological processes including inflammation, regulation of blood pressure and fluid and electrolyte balance (Reviewed in Ref. 1). BK induces a profound hypotensive. effect in vivo and dilates the arterioles and constricts veins in vitro. From the pharmacological experiments using isolated strips of blood vessels, uterus and intestine, it has been shown that BK exerts its effects by interacting with two different types of receptors for BK, ie. B1 receptors such as in rabbit aorta, and B2 receptors such as in cat ileum and rat uterus3).
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