Abstract
Pigs were immunised intraperitoneally with ovalbumin in Freund's complete adjuvant and subsequently challenged intratracheally with ovalbumin. The results show that the group receiving two intratracheal challenges had a significantly greater antiovalbumin-containing cell response in the lamina propria of the respiratory tract. With intraperitoneal immunisation or intratracheal challenge alone the response was negligible. The immunoglobulin isotype of the anti-ovalbumin containing cells was predominantly IgG. There was also a substantial antibody containing cell response in the lung which was also IgG. These findings are discussed in relation to immunity within the porcine respiratory tract.
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