Abstract

A GC–MS method has been developed to determine two methylated arsenic species in human urine samples. This GC–MS method was compared with high-performance liquid chromatography–hydride generation–atomic fluorescence spectrometry. The yield of derivatisation for dimethylarsinic acid (DMA) and monomethylarsonic acid (MMA) using thioglycol methylate was measured. The detection limits for DMA and MMA using this GC–MS method are 0.95 and 0.8 ng/cm 3, respectively.

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