Abstract
Histochemical Stains Dual staining with hematoxylin, which stains nuclei blue, and eosin, a pink cytoplasmic stain, is the mainstay in routine examination of cutaneous tissue under light microscopy. The ability to delineate differences in tissue type and cellular components is greatly enhanced by exploiting the inherent uptake properties of various tissues with these stains. When particular characteristics are not easily identified with hematoxylin and eosin, histochemical staining becomes of great value. Its merit is recognized diagnostically and economically, as histochemical staining is much less expensive than immunohistochemical staining and is readily available in virtually all dermatopathology practice settings.
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