Abstract
Special Issue on Testis Cancer
Highlights
Most patients can be cured, some of them by orchidectomy alone, some by a combination of cisplatinbased therapy and surgery. This demands precautions in the treatment recommendations focusing on long-term rather than short-term toxicity in this young patients’ population and alternatives to the cisplatin-based therapy are warranted
A small entity of germ cell tumors harbors treatment-resistant cell clones, which need to be identified as early as possible and characterized on a molecular level to identify the underlying mechanisms of therapy-resistance. Even patients with such resistant disease patterns can be cured. All this implies that physicians treating patients with germ cell tumors need to be counseled, second opinion before treatment should be standard and advanced metastatic patients need to be treated in highly specialized centers
Many of the above-mentioned prerequisites to treat patients suffering from germ cell tumors with cutting-edge knowledge and technology are presented by international experts in the field
Summary
Most patients can be cured, some of them by orchidectomy alone, some by a combination of cisplatinbased therapy and surgery. This demands precautions in the treatment recommendations focusing on long-term rather than short-term toxicity in this young patients’ population and alternatives to the cisplatin-based therapy are warranted.
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