Abstract
Abstract Adolescent and young adult (AYA) patients are a small, but very important, group of cancer patients to focus on because they have historically been underrepresented in clinical trials and they have unique care needs that, if unaddressed, lead to poorer long-term survival outcomes and quality of life. Pelvic radiation therapy (RT) is frequently utilized in treatment paradigms for pelvic cancers, and treatment can lead to several acute and late side effects in patients. Some of these side effects can be especially impactful in AYA female cancer patients, including issues surrounding fertility and premature ovarian insufficiency, sexual health, financial toxicity, and psychological impact on body image, relationships, and other facets of a young person’s life. An understanding of how pelvic RT can specifically affect AYA patients can help radiation oncologists to better counsel patients and take proactive steps to help mitigate side effects, as well as make referrals to other specialists who are equipped with resources that may help improve the AYA patient’s long-term quality of life and survivorship.
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