Abstract
Aim : to assess special characteristics of disease course, development of concomitant diseases and enzymatic status of gastro-intestinal tract in children with chronic gastroduodenitis, living over the territory of Kursk magnetic anomaly. Patients and methods: 120 children with confirmed diagnosis of chronic gastroduodenitis (among them 60 patients from Kursk and 60 patients from Zheleznogorsk) were performed complex clinical examination. Results: the prevalence of gastroduodenal disorders were 2,7 times higher among children from Zheleznogorsk, than among children from Kursk. Early beginning of chronic gastroduodenitis in children of Zheleznogorsk must be mentioned. The mean age of the onset of the disease in Kursk is 6,4±0,4 years, while in Zheleznogorsk — 5,0 ± 0,4 years (p < 0,01). The most common concomitant diseases in Zheleznogorsk children were reactive changes of hepatobiliary system and combination of chronic gastroduodenitis with allergic pathology. On coprological test the majority of Zheleznogorsk patients had significantly higher content of fatty acids in faeces. Conclusions : the above-mentioned changes can be evidence of insufficient enzymatic activity of certain components of digestive juices. Children with chronic gastroduodenitis living over the territory of Kursk magnetic anomaly should be isolated into a separate group of patients. It will allow rational correction of standard schemes of treatment with accordance to established characteristics.
Highlights
ВВЕДЕНИЕ Заболевания желудка и двенадцатиперстной кишки являются наиболее распространенными из всех болезней органов пищеварения у детей и составляют
Children with chronic gastroduodenitis living over the territory of Kursk magnetic anomaly should be isolated into a separate group of patients
Эти изменения встречались у 27 (45%) жителей Курска и 39 (65%) человек из Железногорска
Summary
Aim: to assess special characteristics of disease course, development of concomitant diseases and enzymatic status of gastro-intestinal tract in children with chronic gastroduodenitis, living over the territory of Kursk magnetic anomaly. The most common concomitant diseases in Zheleznogorsk children were reactive changes of hepatobiliary system and combination of chronic gastroduodenitis with allergic pathology. Children with chronic gastroduodenitis living over the territory of Kursk magnetic anomaly should be isolated into a separate group of patients. It will allow rational correction of standard schemes of treatment with accordance to established characteristics. При этом снижение относи- жизни и болезни. Всем детям проведено комплексное клинико-лабола случаев заболеваний желудочно-кишечного тракта раторное и инструментальное обследование, включаву детей в Российской Федерации. 85–90% случаев оно носит сочетанный характер, что указывает на общность механизмов их развития [11]
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