Abstract
Abstract The nucleotide sequence of SPC 18 cDNA2 (GenBank accession number J05466) encodes a 179 amino acid polypeptide with a calculated molecular mass of 20,626 Da. SPC 18 and SPC 21 (seep. 90) are products of separate genes, yet their amino acid sequences are strikingly similar. In a 176 amino acid region of overlap between the two proteins, no insertions or deletions are present and identity exists at 143 or 81% of amino acid positions. The most dramatic primary structure differences between the two proteins exist at the amino terminus where the SPC 21 primary translation product possesses 11 additional amino acids not present in SPC 18, and in an internal region of the protein where 4 acidic residues in SPC 21 appear as neutral or basic amino acids in SPC 18 (Asp117 to Gin105, Asp120 to His108, Glu131 to Ala119, and Glu140 to Gln128).
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