Abstract
We demonstrate a method for the spatial tracking of individual particles, dispersed in a fluid host, via Raman spectroscopy. The effect of moving a particle upon the intensity of different bands within its Raman spectrum is first established computationally through a scattering matrix method. By comparing an experimental spectrum to the computational analysis, we show that the position of the particle can be obtained. We apply this method to the specific cases of molybdenum disulfide and graphene oxide particles, dispersed in a nematic liquid crystal, and contained within a microfluidic channel. By considering the ratio and difference between the intensities of the two Raman bands of molybdenum disulfide and graphene oxide, we demonstrate that an accurate position can be obtained in two dimensions.
Highlights
We demonstrate a method for the spatial tracking of individual particles, dispersed in a fluid host, via Raman spectroscopy
By containing particles in a microfluidic cavity during spectroscopic analysis, we introduce additional contributions to the spectral signature owing to the properties of the cavity itself[19,20,21]
The microfluidic channels are etched into the top silicon layer and terminate at the silicon dioxide boundary
Summary
We demonstrate a method for the spatial tracking of individual particles, dispersed in a fluid host, via Raman spectroscopy. To optimise the microfluidic design for facilitating strong confinement of incident light within the channel and to significantly enhance the back-scattered Raman signal ‘emitted’ (Fig. 1b) after interaction with the individual incorporated particles, one can model the variation in the intensity of the Raman bands of the dispersed particles while varying parameters that can be experimentally controlled.
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