Abstract
The article provides the spatial aspects of the effectiveness improving of the national innovation system. The role of regional innovative spillovers in the development of innovative activity is determined. The question is raised about the prerequisites for the knowledge flow between the last two. The internal morphology of the innovative space is analyzed to identify the territorial features of knowledge spillovers, based on the frame and center-peripheral approaches. The problems of the unevenness of innovative activity in Russian regions are considered, zones of the center, semi-periphery and periphery of the innovative space of the country are identified. The lack of innovative cores, the large distances between existing ones do not allow to form a full-fledged innovative framework of the country, creating conditions for the diffusion of innovations and the flow of knowledge. In conclusion, directions are proposed for reducing the spatial polarization of innovation and increasing the potential for the impact of innovative spillover effects on the sustainability of regional innovation systems
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