Abstract

<h3>Conflict of Interest</h3> None of the Authors has any financial/commercial conflicts of interest with the published data. <h3>Acknowledgement</h3> This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Herniated lumbar discs are a common cause of low-back pain and decreased quality of life, especially in the productive age population. Currently, in addition to the classic open discectomy, minimally invasive percutaneous endoscopic lumbar discectomy (PELD) is also a valid treatment option. This study was aimed to assess changes in the quality of life after PEDL in patients with sciatica in the Slovak and Czech republic. The study included 470 patients who underwent transforaminal, interlaminar or translaminar endoscopic discectomy. Evaluation of changes in pain perception and quality of life was made by comparing statistical weight values in EQ-5D-5L, quality of life (EQ-VAS), Oswestry disability index (ODI), and numerical scales of leg pain and back pain grading questionnaires before the endoscopic surgery and 12 months after. Comparison of ODI, EQ-VAS and numerical pain scales showed a significant improvement in the reduction of back pain and leg pain. All evaluated dimensions of the EQ-5D-5L questionnaire indicated a significant improvement in the assessed quality of life (p &lt;0.001). Outcomes of assessments of the quality of life via selected questionnaires showed that the efficacy of PELD is comparable to any type of open spine surgery. In addition, patients after PELD showed no signs of surrounding muscular tissue damage on postoperative MRIs. By comparing transforaminal, interlaminar or translaminar approaches, we did not observe any differences between different surgical techniques and no difference in the percentage of postoperative complications or re-herniation rates.

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