South Ural state medical University, Department of Dermatovenerology

Abstract

The article discusses modern ideas about the role of microbial agents in the pathogenesis of the most common dermatoses in pediatric practice. The paper shows the importance of the skin microbiome and foci of chronic inflammation in the induction and maintenance of the pathological process in the dermis in atopic dermatitis, psoriasis. Presented own clinical observations of two girls at the age of 1 2 years with a diagnosis: vulgar psoriasis with lesions of the skin, scalp, and at the age of 5 years with a diagnosis of atopic dermatitis, childhood phase, erythematous-squamous form, mild course. The preparation of activated zinc pyrithione has anti-inflammatory, antifungal and antimicrobial activity, a high safety profile and can be used to control inflammation and correct the skin microbiome. The use of the preparation of activated zinc pyrithione significantly reduces the need for external corticosteroids.