Sorbate-sorbent interactions of nitrogen heterocycles in gas chromatography : Pyridine derivatives

Abstract

The gas chromatography of a wide variety of pyridine and benzene derivatives was carried out. The sorbate-sorbent interactions of 3-substituted pyridines and 4-alkylpyridines were similar to those in the benzene derivatives; the retention times of the more readily available benzene compounds could accurately predict the retention times of 3-substituted pyridines. Similar relations with other pyridines were complicated by steric effects and by direct resonance interactions between substituents and the ring nitrogen.