Abstract

Ocular diseases are one of the main causes of irreversible disability in people in productive age. In 2020, approximately 18% of the worldwide population was estimated to suffer of diabetic retinopathy and diabetic macular edema, but, unfortunately, only half of these people were correctly diagnosed. On the other hand, in Colombia, the diabetic population (8% of the country’s total population) presents or has presented some ocular complication that has led to other associated costs and, in some cases, has caused vision limitation or blindness. Eye fundus images are the fastest and most economical source of ocular information that can provide a full clinical assessment of the retinal condition of patients. However, the number of ophthalmologists is insufficient and the clinical settings, as well as the attention of these experts, are limited to urban areas. Also, the analysis of said images by professionals requires extensive training, and even for experienced ones, it is a cumbersome and error-prone process. Deep learning methods have marked important breakthroughs in medical imaging due to outstanding performance in segmentation, detection, and disease classification tasks. This article presents SOPHIA, a deep learning-based system for ophthalmic image acquisition, transmission, intelligent analysis, and clinical decision support for the diagnosis of ocular diseases. The system is under active development in a project that brings together healthcare provider institutions, ophthalmology specialists, and computer scientists. Finally, the preliminary results in the automatic analysis of ocular images using deep learning are presented, as well as future work necessary for the implementation and validation of the system in Colombia.

Highlights

  • Ocular imaging has been continuously evolving and constitutes a useful tool in the clinical care of patients with retinal diseases

  • optical coherence tomography (OCT) uses low coherence light interferometry to create a detailed image of retinal and choroidal layers [2]. Both are widely used for the detection and treatment of diabetes-related eye diseases, such as diabetic retinopathy (DR) and diabetic macular edema (DME)

  • SOPHIA's design is driven by particular design objectives and constraints: the solution must be focused on its low cost, using free software tools, open-source code, and low hardware requirements; the solution must support images from conventional ophthalmic imaging devices and low-cost acquisition devices (3D printing); access to images should support different mechanisms from conventional text search of image metadata to retrieval mechanisms based on visual content, and, an interface that supports different types of users and platforms must be provided

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Summary

Introduction

Ocular imaging has been continuously evolving and constitutes a useful tool in the clinical care of patients with retinal diseases. Over the last few decades, the use of different imaging techniques has provided a very detailed description of several retinal diseases. Ocular images are essential for the prognosis, diagnosis, and follow-up of patients with retinal diseases. OCT uses low coherence light interferometry to create a detailed image of retinal and choroidal layers [2]. Both are widely used for the detection and treatment of diabetes-related eye diseases, such as diabetic retinopathy (DR) and diabetic macular edema (DME). This article presents the general architecture of a system based on deep learning techniques, called SOPHIA, for the diagnosis of eye diseases. The system supports different types of acquisition devices, in particular portable and low-cost devices based on a conventional smartphone

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