Abstract
This study aimed to develop sonothermogenetics for noninvasive, deep-penetrating, and cell-type-specific neuromodulation by combining a thermosensitive ion channel TRPV1 with focused ultrasound (FUS)-induced brief, non-noxious thermal effect. Sonothermogenetics is a noninvasive and cell-typespecific neuromodulation approach with the capability to target the deep brain.
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