Abstract
Background : Fatty liver (chronic liver disease) was most frequently found associated with gall stones. It arises due to accumulation of lipid in hepatocytes mainly triglyceride. Due to high existence of obesity in the population, the risk of fatty liver and gall stones also increases. In Pakistan the prevalence of fatty liver was 15-20 %. Fatty liver and gall stones could easily be observed on ultrasound. Objective: To evaluate the sonographic association between fatty liver and gall bladder Stone. Study Design : Descriptive Study was conducted Settings: Sanabil health services. Lahore Period: Four months Material & Methods: In our study patients presents with epigastric pain high cholesterol level and previous history of gall stones.While patient with the history of cholecystectomy were excluded. All the data had been composed from Sanabil Health Services Lahore. After informed consent, data was composed through ultrasound machine GE LOGIQ P7 with convex probe (frequency 2.5- 5MHZ) Results: According to results total volume of patient was 220. Now we were comparing between cholelithiasis and grading of fatty liver. Total no of GRADE 1 fatty liver patients were 63 out of 220 in which 13 patients were showing absence of GS while 50 patients showed GS. Total no of GRADE II fatty liver patients were 89 out of 220 in which 36 patients were showing absence of GS while 53 patients showed GS. Total no of GRADE III fatty liver patients were 68 out of 250 in which 20 patients were showing absence of GS while 48 patients showed GS. Total no of 69 out of 220 patients showed absence of GS while 151 patients out of 220 showed with GS. Conclusion: We concluded that the patients who had high cholesterol level, gall stones are associated with fatty liver disease. Moreover fatty liver disease was more common in females than males. Keywords : Nonalcoholic fatty liver, chronic liver disease, Gallbladder, Gall stones, Ultrasound and cholecystokinin. DOI: 10.7176/JHMN/91-09 Publication date: July 31 st 2021
Highlights
Diabetes, hyperlipidemia, and hyperinsulinemia are the predisposing factors for fatty liver and gallstones1,2,3.subsequently of reduced gallbladder motility and enlarged bile lysogenicity, patients with gallstones might be at risk of emerging fatty liver 4
Fatty acid metabolism problems are accountable for pathogenesis of hepatic steatosis, which may be because of disproportion in energy intake and it’s burning, resulting in lipid storage in the liver[12]
Non alcoholic fatty liver disease was found in 62.5 percent (n = 55) of the participants, while metabolic syndrome was found in 28.4 percent (n = 25). 26.94 percent has a BMI of lesser than 18, 32.12 had a BMI of 18 to 25, and 40.93 percent has a BMI of more than 25
Summary
Diabetes, hyperlipidemia, and hyperinsulinemia are the predisposing factors for fatty liver and gallstones1,2,3.subsequently of reduced gallbladder motility and enlarged bile lysogenicity, patients with gallstones might be at risk of emerging fatty liver 4. It occurs from the assemblage of lipid in liver cell mostly triglyceride[5,6].This condition can turn into more worst like liver cirrhosis. In community the prevalence of the fatty liver in South-Asia and the South. There are certain risky reasons associated with fatty liver disease like, obesity, high dietary intake, diabetes mellitus type II. NAFLD is the most likely cause of cryptogenic cirrhosis, since it can lead towards cirrhosis or Hepatocellular-Carcinoma (HCC)[14]
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