Abstract

An efficient synthesis method based on three-component condensation of various aldehydes, methylene active compounds and phenylthiourea (urea) in the presence of hydrofluoric acid has been developed and some of their transformations have been carried out. An efficient method has been developed for the synthesis of some derivatives of tetrahydropyrimidine-5-carboxylates based on the three-component condensation of various aldehydes and β-diketones with thiocarbamide. The antioxidant properties of the synthesized compounds were studied in model reactions by the kinetic method.

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