Abstract

1. 1. A study of the electrophoretic mobility of Matt and Glossy variants of Streptococcus pyogenes, Type 6, during growth in liquid medium, revealed changes that could be correlated with the accumulation of hyaluronic acid on the bacterial surface during the active growth phase followed by its removal during the stationary phase. 2. 2. The hyaluronic acid is firmly attached to the surface of the Matt variant, but is easily removed, by washing, from the Glossy variant. 3. 3. The pH-mobility curves of the two variants suggest that a protein-hyaluronic acid complex may form an important part of the streptococcal surface.

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