Abstract

The effects of halothane have been studied in conscious and unanaesthetized fowls. Halothane evoked a fall in blood pressure. In chickens with a mesencephalic transection a rise in blood pressure preceded the fall due apparently to a discharge over sympathetic nerves. Halolhane depressed respiration. The pCO 2 content of arterial blood rose during halothane anaesthesia. Body temperature fell during the administration of halothane more markedly in young than in adult chickens; recovery of temperature was more rapid in adult fowls. Electrocortical desynchronization occurred on commencing halothane. This was replaced by large amplitude 1–4 c/s electrocortical potentials as halothane was continued. Halothane depressed a lower limb crossed extensor reflex and abolished the electromyogram. There was little effect on the neuromuscular junction despite potentiation of the neuromuscular blocking effects of tubocurarine.

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