SOME PATHOLOGICAL AND IMMUNOHISTOCHEMICHAL STUDIES ON PASTEURELLA MULTOCIDA AND ARCANOBACTERIUM PYOGENES IN BOVINE LUNGS

Abstract

P. multocida and A. pyogenes were detected in twenty six and thirteen out of forty pneumonic lungs (62.5% and 32.5%) respectively. Higher frequencies of lung infection were caused by serotypes A and D. In twelve lungs immunolabelled for P. multocida and A. pyogenes, the antigen of the latter was more frequently associated with serotypes A and D. P. multocida serotypes A&D and A. pyogenes were mostly associated in variable intensity with lungs affected with fibrinosuppurative, suppurative and necrotizing bronchopneumonias. Furthermore, in lungs affected with multifocal areas of necrosis one or both bacteria were stained as intracellularly inside the cytoplasm of PMNs and macrophages surrounding the area of necrosis and/or extracellularly in the necrotic center, most commonly, caseopurulent ,