Some Observations of the Pancreatic Secretion in a Dog

Abstract

Some kinds of food-stuffs used in this country, with beef, bread and milk, much investigated by previous workers, were given to a dog indefinitely well surviving preparation of the pancreatic fistula, in the amount corresponding to one-third of the basal metabolism per diem re the fuel value. In general the carbohydrate rich diet brings about a somewhat greater secretion of the pancreatic juice and the secretion continues much longer in comparison to the other two kinds of diet: among the latter the protein rich diet causes a little greater secretion than the fat rich one, but there is no significant difference. Mixed diet occasions pancreatic secretion in correspondence to its composition. Fish acts with quite the same effect as flesh r_??_ the pancreatic secretion, just as r_??_ the gastric secretion, contrary to the previous investigator. It is worthwhile to note that a carbohydrate rich diet elicites only small secretion of gastric juice (Hirohata), contrary to the previous well known results, while it elicites an abundant secretion of pancreatic juice. This is rather comprehensible if kinds of ferments contained in those juices be taken into account. It seems desirous to test to what extent the spontaneous liberation of pancreatic juice is due to conditional reflexes, and further to know if there is some portion of spontaneous liberation which is independent from nervous mechanism, what inhibitory influence will be established by psychical disturbance upon this portion of secretion.