Some Observations of the Gastric Secretion in Dogs on Fictitious Feeding

Abstract

The present report consists of the data, yielded in the dogs with the stomach fistula or the Pavlov pouch, with the esophageal fistula. Further, in such a dog the Eck fistula was prepared, and in another the portal vein was constricted above the upper mesenterial vein. The results may be summarized as follows: In the gastric secretion the cephalic phase makes the essential portion in the whole course, especially its former part being chiefly, at least, of the nervous origin. The facts, that a certain food-stuffs, such as plain boiled rice, fermented soja-beans, etc, are incapable in certain dogs to cause an abundant output of gastric juice, are solely due to the fact that they evokes only poor appetite. If those dogs will be accustomed to take those food-stuffs, then gastric secretion will be increased by and by, and finally reach maximum amount just as by other stuffs, which evoke always good appetite, and accordingly an abundant outflow of gastric juice. The fact that the fictitious feeding of a brief period, such as 3 minut;s, causes a long continuned secretion of gastric juice, such as two to three hours, contrary to a brief secretion of saliva, such as 5 minutes, on the same procedure, shows a long persistence of the central mechanism of gastric secretion. In accordance with this fact the conditional reflex of gastric secretion does not disappear easily, after the conditional stimulus has been discontinued, but continues considerably long, also contrast to the salivary secretion. The establishment of the Eck fistula incrases the gastric secretion on the fictitious feeding, but only in the latter half of the secretion period, and in a relatively small amount, contrary to the experiments with the Pavlov pouch. On the other hand, the constriction of the portal vein above the mesenterial vein causes an abundant outflow of gastric juice, just as from the dog with the Pavlov pouch and the Eck fistula. Some considerations or further experiments are needed to explain both data, just mentioned, and the data on the gastric secretion from the dogs with the Eck fistula, reported by Lebedinskaja, Gerez and Weiss, Murata (3), and Ka (2), altogether.