Abstract
The subject of specific organotherapy in the treatment of blood diseases was reopened by two observations in the treatment of anemia. The first was that of Whipple, Hooper and Robscheit, 1 who noted that liver and kidneys were more effective than other organs in the dietary treatment of the anemia of hemorrhage in dogs. Later, Minot and Murphy 2 found that these organs were even more specific in treating the totally different type of anemia in man, pernicious anemia. Unlike diseases of the thyroid, pituitary, suprarenal and pancreas, the feeding of the specific organ or its extracts (bone marrow, spleen) did not prove as effective in relieving anemias or blood dyscrasias as had at first been hoped. Leake 3 reported good results with feeding freshly prepared spleen and bone marrow, but the results in pernicious anemia were not as striking as those following liver therapy. The successful use of totally
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