Abstract
We retrospectively assessed whether there was a relationship between lung complications and some easily accessible markers to predict the presence of pulmonary consolidation in patients with coronavirus disease 2019 (COVID-19). According to the polymerase chain reaction and chest computerized tomography results, the study was categorized into three groups. Group 1 (n=87) included the patients with polymerase chain reaction (+), group 2 (n=55) included the patients with polymerase chain reaction (-) and chest computerized tomography (+), and group 3 (n=77) included the patients with polymerase chain reaction (-) and chest computerized tomography (-), respectively. High-sensitivity C-reactive protein and increased age were associated with higher computerized tomography (CT) scores. Increased age and C-reactive protein (CRP) may suggest pulmonary infiltration on chest CT in patients with COVID-19.
Highlights
The novel coronavirus, severe acute respiratory syndrome coronavirus (SARS-CoV-2), had an epidemic potential in 2019 and spread all over the world, with its status changing to a pandemic[1,2]
After having been approved by the local Ethics committee, the study was retrospectively conducted in patients who were admitted to the emergency department and treated after a diagnosis of SARS-CoV-2 from April 2020 to August 2020
All samples for real-time polymerase chain reaction (RT-PCR) assays were obtained from a nasopharyngeal swab
Summary
The novel coronavirus, severe acute respiratory syndrome coronavirus (SARS-CoV-2), had an epidemic potential in 2019 and spread all over the world, with its status changing to a pandemic[1,2]. One of the main problems was a hyperactive-immune response that propagates lung dysfunction and atheroembolic events[4,5]. For this reason, many studies have been conducted to detect real pathophysiological problems. Infections and inflammatory events cause some systemic reactants to be released, like CRP, procalcitonin, transferrin, into the body within hours or days. Since patients with COVID-19 pneumonia have a secondary infection, especially after ventilatory use, the possibility of lung disease should be considered[6]. These acute-phase reactants can be further increased in case of secondary infection
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
