Abstract
With increasing use of radiofrequency (RF) ablation in the treatment of liver cancer,more clinical problems are encountered.Translational research is urgently needed to solve these problems which include:(1) RF needle functional characteristics; (2) effects of RF ablation on liver cancer related changes in pathology; (3) changes in invasive ness and metastatic potential of residual liver cancer cells after incomplete ablation,and their mechanisms; (4) changes in tumor-associated endothelial cell function in residual liver cancer tissues after incomplete ablation,and their mechanisms; (5) prevention and treatment of residual liver cancer after RF ablation; (6) changes in the host's antitumor immunity after RF ablation of liver cancer. Key words: Liver cancer; Radiofrequency ablation; Translational medicine
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