Abstract

The use of ethylation in the study of naturally occurring glycosides and partial methyl ethers of hydroxy flavones is discussed. This procedure renders the work simpler and more definite. Starting from ω-ethoxy res-and phloracetophenones, the preparation of mixed ethyl methyl ethers of the flavonols, fisetin, kaempferol, and quercetin, with an ethoxyl in the 3-position and methoxyls in the other positions, is described and it is shown that these compounds are useful in the study of the 3-glycosides of these flavonols. The case of rutin has been used as a typical example.

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