Some Hematological Parameters In Malaria Parasitaemia

Abstract

Differential white blood count in children between the age of 5-10 years in Owerri was investigated in 50 malaria positive children and 20 age matched children who were negative for malaria. Their differential count where estimated in addition with their PCV and platelet. The mean total white blood cell count was also estimated the result obtained shows that The mean total white blood cell count was significantly lower in malaria subjects than in non infected subjects (5.1±0.98), (7.9 ± 1.2), (p<0.05) the results obtained also shows that neutrophil count of infected subjects (42.7± 7.90) was significantly lower (P<0.05) when compared with that of non infected subjects (49.0±8.60). The mean value of lymphocyte count of malaria subjects was significantly increased (p<0.05)(52.5±9.35) when compared with non infected subjects (48.9±8.80). The mean value of eosinophil count of malaria subjects was significantly increased (2.2±0.49) when compared with non infected subjects (1.1±0.27). The mean value of monocyte was significantly increased in malaria infected subjects (3.3±0.66) when compared with non infected subjects (1.0±0.25), (p<0.05). The PCV and platelet of infected subjects respectively were significantly decreased when compared with that of non infected subjects (p<0.05). Conclusively, malaria parasite infection affects almost all the blood cells.