Abstract
Figure 1. Some Features of Fanconi's Anemia. The physical and cytogenetic findings in some patients with Fanconi's anemia are shown. Panel A shows the characteristically short thumb; Panel B shows a cafe au lait spot; and Panel C shows chromosomal breaks as revealed by cytogenetic analysis (A indicates chromatid breaks, B chromatid fragments, and C a dicentric chromosome). Other common clinical manifestations include short stature, skin hyperpigmentation, pancytopenia, and renal anomalies.
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