Some etiopathogenetic features of dogs’ breast tumors

Nikolay Krasnoslobodtsev,Tatyana Alymova,Natalya Kuharenko,Evgeny Shapiro

doi:10.1051/e3sconf/202020301014

Nikolay Krasnoslobodtsev, Tatyana Alymova + Show 2 more

Open Access

https://doi.org/10.1051/e3sconf/202020301014

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Abstract

The article presents data on the epidemiological features of breast cancer in dogs, namely: the frequency of oncological pathologies in dogs in 2017-2019, the structure of oncological diseases, studied the age-sex characteristics of breast tumors, the frequency of certain risk factors leading to the development of breast neoplasms in dogs. From this study, it was found that neoplasms occurred in 4.8% of the dogs admitted to the clinic. In dogs, a mammary gland tumor was recorded in 153 individuals оf which, 150 females and 3 males. Breast tumors ranked first in localization (28% of all tumors), and skin tumors ranked second (8.5% of all tumors). In females, the first place is a breast tumor (45%), in males - skin tumors (13%). In most animals, the size of a breast tumor at its primary detection corresponded to the T2-T4 stage according to the TNM classification, and in some cases T4a-d. Out of 150 females with breast tumors, only 40 were castrated. This justifies the need for the formation of approaches to early diagnosis of breast tumors in domestic dogs, as well as to the study and prevention of risk factors.

Highlights

More and more often in the practice of a veterinarian there are patients with breast tumors, and the relevance of work in the direction of studying this pathology is determined by several factors
The second factor is the interest in comparing tumors of domestic animals and humans, since the study of mammary gland tumors in dogs as a “model” played a large role in the formation of knowledge about the essence of the tumor process [12]
Neoplasms of all types with different localization were detected in 549 dogs out of 11575 admitted to the Druzhok veterinary clinic both for treatment and for various examinations and for various planned manipulations, including vaccination

Summary

Introduction

More and more often in the practice of a veterinarian there are patients with breast tumors, and the relevance of work in the direction of studying this pathology is determined by several factors. There are contradictory data on the relationship of reproductive status with the development of breast tumors, on the breed predisposition to the oncological process, there is little information about the role of the conditions of keeping animals, and there are practically no data on the state of immunity. According to Yakunina M.N. and a number of other authors, cats most often have lymphomas and skin tumors, and breast tumors are in third place, while dogs have breast tumors in second place after skin tumors It is known from this source that in castrated female dogs before the first estrus, breast tumors are much less common [1, 3, 4]. It should be emphasized that it is epidemiological studies that allow us to establish the relationship between tumors and various causative factors, including environmental ones, to identify risk groups, to study the structure of the pathology, its age-gender and breed characteristics

The aims and objectives of the study

Materials and research methods

Results and discussion

Conclusions