Abstract
The effects of subcortical electrical stimulation on electroencephalographic activity, physiologic reactions, and spontaneous behavior of animals have received considerable attention. In 1949 Moruzzi and Magoun13reported that stimulation of the reticular formation of the brain stem produced a low-voltage fast electroencephalogram, characteristic of the alert state. These effects might be mediated in part by the diffuse projection system of Jasper.8Ingram, Knott, and Chiles7showed that, in the unanesthetized animal, stimulation of the reticular system would evoke behavioral, as well as electrical, alerting. Hess4,5has studied at length the effects of diencephalic stimulation on the spontaneous behavior of the unanesthetized animal and obtained a variety of responses, both autonomic and somatic in nature. Using anesthetized cats, Kaada10elicited both autonomic and somatic responses from stimulation of rhinencephalic structures, but failed to evoke any autonomic reactions from stimulation of the hippocampus. MacLean and Delgado11
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