Abstract
The effects of a variety of nutritional deficiencies on antibody formation in rats have been studied. Deficiencies of vitamin B6, tryptophan and phenylalanine in rats decreased the antibody response to the synthetic antigen, poly Glu52Lys33Tyr15 (no. 3) or to the natural antigen, sheep red blood cells. Methionine deficiency, methionine excess, or caloric restriction did not alter the antibody response. The metabolic antagonist deoxypyridoxine further decreased the antibody response in vitamin B6-deficient rats. The effect was reversed partially by glycine or serine, serine being more effective on a molar basis. Ethionine, a methionine antagonist decreased the antibody response, and its effect was not reversed by adenine or by methionine. The antibody response in germfree rats was higher than in normal animals.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
