Abstract
1. The effects of acetylcholine, isoproterenol and noradrenaline on muscular tonus of the small intestine and esophagus of the lizards Liolaemus gravenhorsti and Liolaemus tenuis tennis were studied in vitro. 2. In the presence of propranolol, noradrenaline elicited an increase in muscle tension of small intestine. 3. In experiments where the small intestine was pretreated with propranolol, and after the application of isoproterenol, the addition of acetylcholine produced a significant decrease of the isometric tension of the intestinal muscle. 4. These results suggest the presence of a mechanism able to cause inhibition of muscular tonus in the small intestine, independently from the mediation by α- or β-adrenoceptors.
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