Abstract

Suspensions of small-plaque and large-plaque lines of polyoma virus showed marked differences in the adsorption of virus particles to cells and to the hemagglutinin inhibitor released from cells. Small-plaque virus was more readily adsorbed than large-plaque virus, and this difference could be used as an adjunct to plaque size distribution in determining the predominant plaque type of virus suspensions. The suspensions of large- and small-plaque virus contained similar proportions of “full” particles of buoyant density 1.32 and “empty” particles of buoyant density 1.29.

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