Abstract
Eighty-six tumor tissues of diverse histology and origin were cultured in vitro. Some growth characteristics were studied with the aim of establishing criteria which might help in prognosis. It was found that tumors of identical origin and classification differed in their ability to grow in either cell or tissue cultures and, in the effect of cancer ascitic fluid on their growth and in morphology of the developing cultures. The main group of tumors tested was the invasive duct carcinoma of the breast, in which we found a wide spectrum of morphological variations which ranged from well-organized homogenous cell layers to small colonies of round aggregating cells which detached quickly. These differences will be correlated with the results of the clinical follow-up being done on the respective patients.
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