Abstract

Summary 1. Quantitative data were obtained from ninety-four randomly selected 7-year-old children and forty caries-free children with respect to the following characteristics: blood urea, salivary urea, salivary ammonia, salivary urea plus ammonia, increase in ammonia nitrogen after two hours' incubation, decrease in urea nitrogen after two hours' incubation, salivary urease activity, the cumulated caries score, and the annual caries increment. 2. A significant correlation was noted between blood urea nitrogen and salivary urea and ammonia nitrogen. 3. In the randomly selected chilren urea in blood, ammonia in blood and saliva, the rate of production of ammonia or the rate of breakdown of urea, and the urease activity did not correlate significantly with dental caries expressed as DMF teeth, DMF and def annual increaments. 4. In a study of forty caries-free children a significantly higher value for blood urea was found as compared to a control. This was interpreted as a reflection of different dietary habits of the two groups with respect to protein and/or carbohydrate intake.

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