Abstract

THE intracellular localization of viable brucella organisms in the tissues of animals and human beings has been of fundamental interest ever since Bang1 announced the etiology of contagious abortion in cattle in 1897. In this initial report from Bang's laboratory, clumps of intracellular bacilli were noted in the uterine exudate removed from a cow with threatened abortion. The intracellular localization of brucella did not appear to attract much attention for a number of years, and then some significant investigations were reported from the laboratory of Theobald Smith in the Department of Comparative Pathology at Harvard Medical School. In 1912 Fabyan . . .

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