Abstract

Since the beginning of the evaluation of plants in terms of human health, the bioactivity properties of plants have been studied in the laboratory and thus standards have been brought to the treatment methods with plants. For this purpose, some bioactive component analyzes of 18 herbal capsules and 2 liquid herbal syrups produced by Naturin Company were performed in our current study. In this context, the total oxidant and antioxidant status of these plant mixtures were evaluated. The free radical capacities of the samples were determined by 1, 1-diphenyl-2-picrylhydrazil (DPPH) method and their DNA protective activities were determined using pBR322 plasmid DNA. Total antioxidant level (TAL) and Total oxidant level (TOL) activities were performed using Rel Assay diagnostic kit. All 3 of the stinging nettle samples showed DNA protective activity. The clean sample containing milk thistle extract also showed DNA Protective activity. In both the syrup samples (My guard and DTX-19) results were detected in the direction of positive protection on DNA. When the DPPH radical scavenging capacity was examined, it was determined that the best results were in juniper, nettle and thistle thistle samples, and the samples with syrup had a very good radical scavenging effect, and all of the samples showed antioxidant activity. This study is a preliminary and supportive study in order to elucidate the properties that can be used as drug active ingredients in traditional medicine, especially in the field of pharmacology.

Highlights

  • Plants are the most important source of natural medicines used in traditional treatment methods

  • When the DPPH radical scavenging capacity was examined, it was determined that the best results were in juniper, nettle and thistle thistle samples, and the samples with syrup had a very good radical scavenging effect, and all of the samples showed antioxidant activity

  • Considering the DPPH radical scavenging capacities, it was determined that the best results were in juniper, nettle and thistle samples, and the syrupy samples had a very good radical scavenging effect

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Summary

Introduction

Plants are the most important source of natural medicines used in traditional treatment methods. In these traditional methods, active substances of plants, which we will describe as secondary metabolites, are used. Active substances of plants, which we will describe as secondary metabolites, are used These secondary metabolites, which are not responsible for the growth and development of the plant, are the active substances of plants [3]. In this way, it has been accepted as a strong possibility that the bioactive substances carried by a plant species with a well-known medicinal value are found in other plant species related to this species, and in this way, the variety of plants that can be used as herbal medicine has increased rapidly. Approximately 25% of prescription drugs in developed countries consist of active ingredients of herbal origin

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