SOME ANAESTHETIC AND PHYSIOLOGICAL EFFECTS OF THIOPENTONE SODIUM IN GOAT KIDS

M A H Ghurashi ,H I Seri ,A.t.h Sobair ,Ashwag E.a.m

doi:10.21608/avmj.2007.178007

M A H Ghurashi , H I Seri + Show 2 more

Open Access

https://doi.org/10.21608/avmj.2007.178007

Copy DOI

Abstract

A total of six healthy goat kids were used in this investigation to study some physiological and anaesthetic effects of Thiopentone sodium at doe level of 10 mg/kg i/v in animals premedicated with acepromazine or diazepam or xylazine and non premedicated animals. Usages of premedication lead to smoother induction of anaesthesia rather than non premedicated animals. Apnoea occurred in the different groups used in this study with significant prolongation in the group anaesthetized with Thiopentone sodium with Xylazine. Respiratory rate, heart rate and rectal temperature were affected to different limits. Usage of the three different premedication drugs especially Xylazine hydrochloride lead to improvement of Thiopentone sodium anaesthetic effects.

Highlights

The importance of goats in many developing countries can be seen in their vital contribution in the production of meat, milk and fresh skin (Payne, 1994)
Apnoea is a common character of Thiopentone anaesthesia (Hall et al, 2006), in this study apnoea occurred in all protocols tested and its duration was exaggerated to a significant levels when the protocol of TH + XY was used, this prolongation may be attributed to the effect of Xylazine which was reported to depress the respiratory system (Aithal et al, 1997) while the other pre anaesthetic medications used were known to have minimal effect on the respiratory system
Muir and Masonen, 1982), the depressive effect of Xylazine on respiratory centres may potentiate the depressive effect exerted by Thiopentone sodium on respiratory centres the significant prolongation of the apnoea duration when this protocols compared with the other protocols used in the study

Summary

Introduction

The importance of goats in many developing countries can be seen in their vital contribution in the production of meat, milk and fresh skin (Payne, 1994). In the Sudan the total population of goats is about 37.346 million head (SBAR, 2000) and they participate efficiently in the national income. It has been established for many years that all surgical procedures are better be done under inhalation anaesthesia (Hall et al, 2006), should the facilities for it are available. Being an ultra –short acting barbiturate, Thiopentone sodium, is a good induction agent producing anaesthesia for a very short duration (Hall and Clark, 1982; Singh and Kumar, 1988; and Batoul, 1990).

Objectives

Results

Conclusion