Somatostatin stimulates coupled sodium chloride influx across the brush border of the rabbit ileum

Abstract

Summary Somatostatin has been previously shown to stimulate Na and Cl absorption in the rabbit ileum in vitro, but the transport pathways involved have not been determined. Therefore, we examined the effect of somatostatin on Na and Cl influx across the brush border of the rabbit ileum. Somatostatin increased Na influx from 3.25 to 4.72 μmoles/cm 2 · hr (p 2 ·hr (p