Somatostatin in Treatment of Acute Recurrent Pancreatitis and Role of Endoscopic Ultrasonography in The Diagnostic Workup

Abstract

The pancreas is an elongated, soft, flat, lobulated, and yellowish gland located on the posterior abdominal wall in a transverse orientation. The structure is located in the retroperitoneum and has a thin capsule. An abrupt response to pancreatic injury is known as acute pancreatitis (AP). Chronic pancreatitis can lead to enduring harm to the composition and the pancreas' endocrine and exocrine functions. The term idiopathic RAP (IRAP) is employed when the reason cannot be readily identified by the assessment of physical examination, medical history, basic laboratory tests (calcium and serum triglyceride levels, for example), and diagnostic imaging studies (e.g., CT scans and transabdominal ultrasounds). With endoscopic ultrasonography (EUS), you may see the inside of your digestive tract and any surrounding tissues in high resolution and real time. When it comes to evaluating a wide variety of benign and malignant GI illnesses, this technique is both efficient and cost-effective. Somatostatin inhibits the release and manufacture of certain enzymes, which in turn decreases the pancreas' ability to absorb amino acids. The release of somatostatin from the pancreatic islets is stimulated by high glucose concentration.