Somatosensory event-related potentials following different stimulus conditions.

Abstract

We studied somatosensory event-related potentials (ERPs) in response to rare target, frequent nontarget and rare nontarget stimuli in 12 healthy subjects. Compared with the corresponding peaks following frequent stimuli, the responses elicited by rare target stimuli showed higher amplitudes for N70, P100 and N140 components and those evoked by rare nontarget stimuli showed higher amplitudes for N70 and N140 components. The P300 component following rare nontarget stimuli was shorter in latency and lower in amplitude than that elicited by target stimuli. ERP waveforms evoked by rare nontarget stimuli also showed obvious N240 and P300 components, which differed from those following frequent nontarget stimuli. These findings suggest that there are differences in signal processing in response to target, frequent nontarget and rare nontarget stimuli. The P300 component was distributed symmetrically and there was no significant hemispheric predominance with regard to any ERP component in response to either right or left side stimulation.