Somatosensory conduction pathway in spastic paraplegia type 5.

Abstract

We describe herein the case of a 37-year-old woman who presented with slowly progressive lower-limb stiffness and gait ataxia. She complained of running difficulties since the age of 10 years, gait impairment since the age of 30 years, and urinary urgency during the past 2 years. Her family history was unremarkable. At the last examination she exhibited spastic gait, pyramidal signs, severe impairment of the vibration sense in the lower limbs, and the Romberg sign. She achieved a Spastic Paraplegia Rating Scale score of 9/52.