Abstract

Aim. To assess somatic comorbidity in male and female cohort with stable angina (sA). Material and methods. Into multicenter, simlutaneous cohort-clinical study, 300 men included (mean age 54±0,4 y.o.) and 230 women (mean age 55,7±0,5 y.o.) with sA of I-III functional class. four institutions participated from Ingushetia Republic. Clinical and instrumental assessment included anthropometry, office blood pressure, heart rate, eCG in 12 leads recording. In fasting venous blood we measured total cholesterol (mM/L) and glucose (mM/L). Results. In cohort of patients with sA the most prevalent are cholelythiasis, gastric and duodenal ulcer disease, chronic diseases of pancreas, separately or together; chronic bulbitis is found in each third person, and urinary lythiasis in 15% of cases. Gastric ulcer and duodenal ulcer diseases, chronic bronchitis and urinary lythiasis are two times more prevalent in men compare to women, but cholelythiasis and chronic diseases of pancreas show the same prevalence among men and women. Among women with sA thyroid diseases are 3 times more prevalent than in men. Conclusion. so, in sA patients comorbidity is quite common. Management and prevention in sA patients cohort should be multifactorial taken a broad spectrum of social and demographic parameters, main risk factors and comorbidities. The key role in coordination and realization of all these activities should be granted to an internist of broad spectrum or general care physician.

Highlights

  • Как известно, желудочковые аритмии у больных ишемической болезнью серд­ца могут быть самого различного происхождения

  • It is known that ventricular dysrhythmias in patients with ischemic heart diasease can be of various origin

  • To check antiarrhythmic abilities of metabolic therapy for ischemic heart disease combined with variety of ventricular arrhythmias of III-IV grades

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Summary

Introduction

Желудочковые аритмии у больных ишемической болезнью серд­ца могут быть самого различного происхождения. В частности, при изучении эффективности имплантированных кардиовертеровдефибрилляторов было выявлено, что тахиаритмии только в 10% случаев предшествовали ВСС, трансформируясь в фатальные, в то время как в 90% — устойчивая желудочковая тахикардия (ЖТ)/фибрилляция желудочков (ФЖ) были лишь механизмом её развития. Эти данные согласуются с теми, в которых летальность была в 3 раза выше в группе больных ИБС и нагрузочными ЖА в сравнении с теми, у кого аритмий при ФН не было [10, 11].

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