Abstract
Molecular modeling of chlortetracycline was performed based on DFT approach implemented in Gaussian software. The differences between simulated electronic spectra and those recorded experimentally were analyzed. Experimental investigations were carried out using electronic absorption spectra as well as fluorescence ones. Spectral shift to the changing of solvent polarity was measured in various solvents (binary solutions) and graphical correlations were evidenced between the electronic band wavenumbers and some theoretical functions on solvent electro-optical macroscopic parameters (refractive index and dielectric constant); interpretation was done based on the solvatochromic theory dedicated to universal interaction forces. Fluorescence spectra, studied in mixture of solvents (ternary solutions), evidenced also specific interactions in water-alcohols not considered in the classical solvatochromic approach.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
