Abstract

This article presents a case of a patient with advanced head and neck cancer, characterized by a large and protruding tumor. The patient was treated with an innovative on-demand online adaptive radiotherapy (ART) technology, guided by cone beam computed tomography (CBCT), on the Ethos adaptive radiotherapy platform(version 1.0, Varian Medical Systems, Palo Alto, CA). Asolutionwas provided for this special case to address the issue where part of the target volume could not participate in the optimization due to exceeding the external contourboundaryduring online adaptive radiotherapy. The treatment outcome was satisfactoryin terms of tumor regression, while only grade 1 radiodermatitis and grade 2 oral mucositisat the end of radiotherapy. This article discusses the clinical diagnosis, treatment process, and follow-up of this case, aiming to provide clinical references for a broader application of this technology.

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