Abstract
Reduced placental perfusion is important in the pathogenesis of both reduced fetal growth and preeclampsia. Our objective was to determine if normotensive pregnancies with delivery of small-for-gestational age (SGA) infants were characterized by abnormal concentrations of circulating angiogenic factors similar to those observed in preeclampsia. We compared serum concentrations of soluble endoglin (sE), sFlt1, and free placental growth factor (PlGF) throughout pregnancy in women wtih SGA infants and normotensive pregnancy to those of women with AGA/LGA infants and normotensive pregnancy.
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