Abstract
Adult T-cell leukemia/lymphoma (ATLL) caused by human retrovirus, HTLV-1, is a neoplasm of mature T-cell. In Japan, more than a thousand patients with ATLL die every year incurable with median survival time less than one year. We aim to investigate clinical value of soluble CD30 (sCD30) levels in sera on prediction of short term mortality and overall survival (OS) in ATLL patients.
Highlights
Adult T-cell leukemia/lymphoma (ATLL) caused by human retrovirus, HTLV-1, is a neoplasm of mature T-cell
We aim to investigate clinical value of soluble CD30 levels in sera on prediction of short term mortality and overall survival (OS) in ATLL patients
Our result suggested that soluble CD30 (sCD30) was the common significant risk factor of chemotherapy and hematopoietic stem cell transplantation (HSCT) in two-year OS
Summary
Adult T-cell leukemia/lymphoma (ATLL) caused by human retrovirus, HTLV-1, is a neoplasm of mature T-cell. Soluble CD30 is a new biomarker to predict two-year overall survival of adult T cell leukemia/lymphoma patients Ratiorn Pornkuna1,2, Shigeki Takemoto1,2,3*, Michihiro Hidaka2,3, Yoshio Haga1,2 From 16th International Conference on Human Retroviruses: HTLV and Related Viruses Montreal, Canada.
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